The Population Health Intervention Research Network (PHIRNET) was a six-year (2009-2015) Strategic Training Initiative in Health Research funded by the Canadian Institutes for Health Research (CIHR). PHIRNET focused on four priority areas in PHIR: methods, economic evaluation, ethics and research governance, and interventions addressing social health inequalities. PHIRNET’s internationally competitive trans-disciplinary training program provided trainees with opportunities to work with Canadian and international experts to develop core competencies related to PHIR. Trainees were also eligible for internships, graduate scholarships and post-doctoral fellowships, and participated in monthly webinars and annual Summer Institute. These opportunities enabled trainees to acquire a comprehensive understanding of PHIR, with special emphasis on training opportunities that require analytical methods and insights that transcend conventional academic boundaries, thereby creating a truly trans-disciplinary training environment.